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Chemopreventive Effects of Korean Red Ginseng Extract on Rat...

The objective of this study was to determine a chemopreventive activity of Korean red ginseng extract (KRG) in diethylnitrosamine (DEN) induced hepatocarcinogenesis in rats. After acclimatization for...

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Use of Proteins as Biomarkers and Their Role in Carcinogenesis

Summary: Improved diagnostic methods and medical therapies are necessary for early detection and treatment and an improved prognosis. It is thus vital to both examine and evaluate the role of the...

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Upregulation of miRNA3195 and miRNA374b Mediates the Anti-Angiogenic...

Recently microRNAs (miRNAs) have been attractive targets with their key roles in biological regulation through post-transcription to control mRNA stability and protein translation. Though melatonin...

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Cancer: We Should Not Forget The Past

Cancer has been in existence longer than human beings, and man has been facing the illness ever since he made his appearance on Earth. Amazingly, the first human cancer gene was cloned only thirty...

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Differentiation between Malignant and Benign Solitary Lesions in the Liver...

Objective: This study was to determine the reliability of age-stratified diagnostic index in differential diagnosis of malignant and benign solitary lesions in the liver using fluorine-18...

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Upregulation of Acetylcholinesterase Mediated by p53 Contributes to...

Background: The expression of acetylcholinesterase (AChE) could be induced during apoptosis in various cell types. And reduced AChE expression either by siRNA could prevent apoptosis. However, the...

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Pathway and Network Approaches for Identification of Cancer Signature Markers...

The advancement of high throughput omic technologies during the past few years has made it possible to perform many complex assays in a much shorter time than the traditional approaches. The rapid...

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Spatial and Temporal Fracture Pattern in Breast and Gynecologic Cancer Survivors

Objective(s): To assess skeletal wide fracture location and time of fracture after cancer treatmentStudy Design: One hundred thirty-nine women diagnosed with breast or gynecologic cancer between 2003...

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ERCC1 Induction after Oxaliplatin Exposure May Depend on KRAS Mutational...

Introduction: Oxaliplatin (Oxa) is widely used in metastatic colorectal cancer (mCRC), but currently there are not valid predictors of response to this drug. In the control arms both of OPUS and PRIME...

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Changes in Bone Density after Cancer Treatment in Patients with Cervical and...

OBJECTIVE: This study aimed to evaluate the impact of cancer treatment on bone mineral density (BMD) in the lumbar spine (LS) and femur in the postmenopausal women with cervical or endometrial cancer...

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Discovery of Invasion Routes for Nasopharyngeal Adenoid Cystic Carcinoma

The aim of this study is to discover regional invasion routes for nasopharyngeal adenoid cystic carcinoma (NACC) through analyses of the magnetic resonance (MR) images and comparison with keratinizing...

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Fibronectin Matrix Formation is a Prerequisite for Colonization of Kidney...

Fibrin plays an important role in lung metastasis. Here we show that fibrin promotes colony formation in primary kidney tumor cells from patients with kidney metastasis. In addition, we found that...

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Colon Cancer Associated Transcript-1 (CCAT1) Expression in Adenocarcinoma of...

Background: Long non-coding RNAs (lncRNAs) have been shown to have functional roles in cancer biology and are dys-regulated in many tumors. Colon Cancer Associated Transcript -1 (CCAT1) is a lncRNA,...

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Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for...

Background: Recent research indicates that long non-coding RNAs (lncRNA) represent a new family of RNAs that is of fundamental importance for controlling transcription and translation. Thereby, there...

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Three-Step Hand-Assisted Laparoscopic D2 Radical Gastrectomy for Chinese...

Three-step hand-assisted laparoscopic D2 radical gastrectomy (HALG) is a modified surgical procedure that has achieved satisfactory results for obese patients in our surgical center. To fully...

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The Quantum of Initial Transformed Cells Potentially Modulates the Type of...

The immune/ inflammation system potentially serves to arrest, eliminate or promote tumor development. Nonetheless, factors that dictate the choice are not comprehensively known yet. Using a B16/F1...

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Could GLUT12 be a Potential Therapeutic Target in Cancer Treatment? A...

Background: Recent studies proposed GLUT12 to be a major glucose transporter involved in the glycolytic metabolism of cancer cells.Methods: GLUT12 expression was determined by immunohistochemistry in...

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The Quality of Tumor Size Assessment by Contrast-Enhanced Spectral...

Background - Contrast-enhanced spectral mammography (CESM) is a promising new breast imaging modality that is superior to conventional mammography for breast cancer detection. We aimed to evaluate...

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Effects of Mitochondrial Translocation of Telomerase on Drug Resistance in...

Hepatocellular carcinoma (HCC) cells exhibit multidrug resistance (MDR), but the underlying mechanisms remain unclear. Cancer cells that overexpress telomerase are resistant to chemotherapeutic drugs....

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The Analysis of the Relationship between Multiple Myeloma Cells and Their...

The bone marrow microenvironment plays a key role in the stimulation of growth and survival of multiple myeloma (MM) cells. We investigated whether membrane microfragments (MFBs) exert a stimulatory...

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