The Assessment of Tumor Response by Measuring the Single Largest Lesion per...
Background: The RECIST 1.1 adopted a total of five target lesions to be measured, with a maximum of two lesions per organ. To the best of our knowledge, the criterion of two target lesions per organ...
View ArticleBrain and Central Nervous System Cancer Incidence in Navarre (Spain),...
Different studies have pointed out Navarre as one of the regions of Spain with the highest incidence rates of brain and other central nervous system (CNS) cancer. Trend analysis for cancer incidence...
View ArticleMiR-217 Promotes Tumor Proliferation in Breast Cancer via Targeting DACH1
Objective: The expression of DACH1 was frequently lost in human breast cancer, which significantly correlated with poor prognosis. Herein, we aim to investigate its underlying mechanisms.Methods: The...
View ArticleClinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in...
Background: Tumorigenesis is a complex process of accumulated alteration in function of multiple genes and pathways. Wnt signalling pathway is involved in various differentiation events during...
View ArticleImmune Suppression during Oncolytic Virotherapy for High-Grade Glioma; Yes or...
Oncolytic viruses have been seriously considered for glioma therapy over the last 20 years. The oncolytic activity of several oncolytic strains has been demonstrated against human glioma cell lines...
View ArticleEnhancement of Intratumoral Chemotherapy with Cisplatin with or without...
Novel therapies for lung cancer are being explored nowadays with local therapies being the tip of the arrow. Intratumoral chemotherapy administration and local microwave ablation have been...
View ArticleMicroRNA-210 and Endoplasmic Reticulum Chaperones in the Regulation of...
Glioblastoma multiforme (GBM) is the commonest primary brain tumour in adults characterized by relentless recurrence due to resistance towards the standard chemotherapeutic agent temozolomide (TMZ)....
View ArticleCullin Family Proteins and Tumorigenesis: Genetic Association and Molecular...
Cullin family proteins function as scaffolds to form numerous E3 ubiquitin ligases with RING proteins, adaptor proteins and substrate recognition receptors. These E3 ligases further recognize numerous...
View ArticleManagement of Inguinal Involvement of Peritoneal Surface Malignancies by...
Background: Achieving complete cytoreduction of peritoneal surface malignancies (PSM) can be challenging. In most cases, delivery of heated intra-peritoneal chemotherapy (HIPEC) is straightforward....
View ArticleNon-invasive Analysis of Genomic Copy Number Variation in Patients with...
To explore new molecular diagnosis approaches for early detection and differential diagnosis of hepatocellular carcinoma (HCC), we analyzed genomic copy number variations (CNV) using plasma cell-free...
View ArticleThe Prognostic Value of Irradiated Lung Volumes on the Prediction of Intra-/...
Purpose: To assess the association between dosimetric factors of the lung and incidence of intra- and postoperative mortality among esophageal cancer (EC) patients treated with neoadjuvant...
View ArticleNumber of Negative Lymph Nodes Can Predict Survival after Postmastectomy...
Purpose: To assess the prognostic value of the number of negative lymph nodes (NLNs) in breast cancer patients with positive axillary lymph nodes after mastectomy and its predictive value for...
View ArticleAmplification of Chromosome 8 Genes in Lung Cancer
Chromosomal alterations are frequent events in lung carcinogenesis and usually display regions of focal amplification containing several overexpressed oncogenes. Although gains and losses of...
View ArticleIntracellular Acidosis Promotes Mitochondrial Apoptosis Pathway: Role of...
Extracellular matrix metalloproteinase inducer (EMMPRIN) is a human leukocyte surface molecule that is enriched on the surface of many cancer cells, and it plays an important role in proliferation and...
View ArticleComplementary Roles of Squamous Cell Carcinoma Antigen and 18F-FDG PET/CT in...
Purpose: To assess the clinical value of FDG PET/CT and evaluate the complementary roles of serum squamous cell carcinoma antigen (SCCAg) and FDG PET/CT in the diagnosis of suspected recurrent of...
View ArticleControlling RECK miR21 Promotes Tumor Cell Invasion and Is Related to...
The search for biomarkers to characterize prostate cancer aggressiveness has been the objective for the majority of researchers involved with the most prevalent tumor in men. MiRNAs are important for...
View ArticleAssociation between CYP1A1 Ile462Val Polymorphism and Oral Squamous Cell...
CYP1A1 Ile462Val polymorphism might play a key role in pathogenesis of oral squamous cell carcinoma (OSCC). Many case-control studies have investigated the association between CYP1A1 Ile462Val...
View ArticleAssociation of Body Mass Index Changes during Neoadjuvant Chemotherapy with...
The purpose of this study was to determine the association between body mass index (BMI) measurements (baseline BMI and changes in BMI during neoadjuvant systemic treatment [NST]) and clinical...
View ArticleYSY01A, a Novel Proteasome Inhibitor, Induces Cell Cycle Arrest on G2 Phase...
Given that the proteasome is essential for multiple cellular processes by degrading diverse regulatory proteins, inhibition of the proteasome has emerged as an attractive target for anti-cancer...
View ArticleInduction of BCL2-Interacting Killer, BIK, is Mediated for Anti-Cancer...
Naturally occurring diarylheptanoid curcumin (CUR), a principal component of the Asian spice turmeric, has been shown to have anti-cancer effects in many tumor types. However, a detailed mechanism...
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